ddPCR™ EGFR Exon 19 Deletions Screening Kit from Bio-Rad

Description

Use the ddPCR EGFR Exon 19 Deletions Screening Kit to screen your samples for the following 15 EGFR Exon 19 Deletions mutations in a single well:

2235_2252>AAT
2235_2249del15
2236_2250del15
2238_2252 > GCA
2238_2255del18
2239_2253 > CAA
2239_2251 > C
2239_2258 > CA
2239_2252 > CA
2239_2256del18
2239_2248TTAAGAGAAG > C
2239_2253del15
2239_2247delTTAAGAGAA
2240_2254del15
2240_2257del18

Key Features and Benefits

Superior performance — allows quantification and screening of 15 EGFR Exon 19 Deletions in a single well
High sensitivity — provides sensitive and precise detection down to 0.5%
Robust workflow — allows screening of multiple samples in a rapid and cost-effective manner

Kit Components

20x ddPCR EGFR Exon 19 Deletions Screening Assay — 1 x 200 µl and ddPCR Supermix for Probes (no dUTP) — 2 x 1 ml (1863023) for screening mutations using the QX200™ or QX200™ AutoDG™ Droplet Digital™ PCR Systems/li>

For extended product descriptions and detailed specification information, please visit Bio-Rad.com.

Product Specs
ItemddPCR™ EGFR Exon 19 Deletions Screening Kit
CompanyBio-Rad
Price Pricing Info Supplier Page View Company Product Page
Catalog Number12002392
Quantity200 rxns
Brand/TrademarkLSG DBG

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Bio-Rad

Bio-Rad Laboratories, Inc. Life Science Research Group 2000 Alfred Nobel Drive

Hercules, California 94547

United States

Phone: 800-424 6723
800-879 2289

Company Profile

Website: http://discover.bio-rad.com

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(1) Detection of EGFR mutation of pulmonary adenocarcinoma in sputum using droplet digital PCRBMC Pulmonary MedicineDecember 1, 2021Tetsuya Isaka, Tomoyuki Yokose, Hiroyuki Ito, Haruhiko Nakayama, Yohei Miyagi, Haruhiro Saito, Munetaka Masudamix to detect the Ex21 using ddPCR. The ddPCR EGFR Exon 19 Deletions Screening Kit (Bio-Rad, Catalog #12002392), which allows the quantification and screening of 15 EGFR exon 19 deletions, was used to detect Ex19.

(2) Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese populationScientific ReportsDecember 1, 2020Anh-Thu Huynh Dang et al.commercially available ddPCR reaction (Bio-rad) was used (ddPCR™ EGFR Exon 19 Deletions Screening Kit #12002392). Statistical analysis Pearson’s chi-squared (χ²) test (sample size >5) or Fisher’s exact test (sample size

(3) Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reactionOncology LettersOctober 29, 2020Kazuya Nishii et al.ddPCR Mutation assay: EGFR p.L858R c.2573T>G (#10049550); ddPCR EGFR Exon 19 Deletions Screening kit (#12002392) and ddPCR Mutation assay: EGFR p.T790M, Human (#10049550). ddPCR was performed at Biobank (Okayama

(4) Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patientsPLOS ONEDecember 16, 2019Le Son Tran et al.commercially available ddPCR reaction (Bio-rad) was used (ddPCR™ EGFR Exon 19 Deletions Screening Kit 12002392). Determination of limit of detection To determine the limit of detection (LOD) for our assays, we

(5) Validation of liquid biopsy: plasma cell-free DNA testing in clinical management of advanced non-small cell lung cancerLung Cancer: Targets and TherapyJanuary 31, 2018Vidya H Veldore, Anuradha Choughule, Tejaswi Routhu, Nitin Mandloi, Vanita Noronha, Amit Joshi, Amit Dutt, Ravi Gupta, Ramprasad Vedam, Kumar Prabhash(deletions) positive, were also verified with ddPCR. ddPCR™ EGFR Exon 19 Deletions Screening Kit, (Cat. no. 12002392) and Cat. no. 10031249: Wild type HEX label (Wt EGFR T790M), Cat. no. 10031246: mutant type FAM label

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